The plant is poisonous.
Application
Celandine has been included in almost all pharmacopoeias as an antidote for poisoning and effective against infectious diseases.
Burdock is a powerful emetic. It is reasonable to assume that it has been used to treat poisoning.
Today, celandine is only used in certain homeopathic remedies.
Ingredients
Vincetoxin, a glycoside with a paralyzing effect on the central nervous system.

Cynánchum vincetóxicum (L.) Pers.
Photo of page in Joachim Burser's herbarium.